Storage and Distribution System for Purified Water: Structure, Parts & GMP Requirements
Storage and Distribution System for Purified Water in the Pharmaceutical Industry
PW Distribution System Components
- Storage Tank: Normally fabricated from SS 316L with sanitizable designs.
- Distribution Loop: There is a continuous flow of water and does not allow for stagnant conditions.
- Pumps: High-quality pumps that give efficient distribution of water through pumps.
- Piping: Sanitary orbital welding on the stainless steel pipelines with sanitary design.
- Microbial Control (UVC/Ozone): For microbial control within the loop.
- Hygienic Point of Use Valves: For hygienic distribution of water.
Considerations for Efficient PW Distribution Systems
Efficient Purified Water Storage and Distribution System involves many important considerations including hygienic operations and efficiency. First, the system is supposed to have a design that involves a loop. This ensures constant flow. There should be temperature control that could either be hot or ambient depending on the purpose of purification. It also involves slope design for complete drainage as well as automated monitoring of parameters like conductivity and TOC.
GMP Guidelines and Compliance
GMP Compliance is mandatory for all PW Distribution Systems. A PW System should be designed, validated, and implemented in compliance with regulatory standards such as USP, EP, and WHO recommendations. Specific GMP guidelines required for a PW Distribution System are listed below:
System design in compliance with hygienic and sanitary principles
Cleanliness maintenance
Validation, documentation, and monitoring of system performance
It goes without saying that using a reputable supplier of PW Systems like Microfinero will ensure that each of your Purified Water Storage and Distribution Systems meets strict pharmaceutical regulations.
